Abstract
Myers, W. F. (University of Kansas, Lawrence) and D. Paretsky. Synthesis of serine by Coxiella burnetii. J. Bacteriol. 82:761–763. 1961.—Enzyme preparations from suspensions of purified Coxiella burnetii are capable of synthesizing serine from formaldehyde and glycine-2-C14 in the presence of tetrahydrofolic acid. Evidence for the reaction is obtained by isolating and identifying radioactive serine and serine derivatives. The data suggest a role for folic acid in these rickettsiae, and extend the knowledge of host-independent biosynthetic competencies of these highly parasitic microorganisms.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- BEHRENS O. K., HOLMES D. H., KLEINSCHMIDT W. J. Vitamin content of purified typhus Rickettsiae, tobacco mosaic virus, and coliphage T6. Biochim Biophys Acta. 1956 Nov;22(2):277–283. doi: 10.1016/0006-3002(56)90152-4. [DOI] [PubMed] [Google Scholar]
- BLAKLEY R. L. The interconversion of serine and glycine: role of pteroylglutamic acid and other cofactors. Biochem J. 1954 Nov;58(3):448–462. doi: 10.1042/bj0580448. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BOVARNICK M. R., SCHNEIDER L. The incorporation of glycine-1-C14 by typhus rickettsiae. J Biol Chem. 1960 Jun;235:1727–1731. [PubMed] [Google Scholar]
- BOVARNICK M. R., SCHNEIDER L., WALTER H. The incorporation of labeled methionine by typhus rickettsiae. Biochim Biophys Acta. 1959 Jun;33(2):414–422. doi: 10.1016/0006-3002(59)90131-3. [DOI] [PubMed] [Google Scholar]
- COHN Z. A. Relation of cell metabolism to infection with rickettsial and bacterial agents. Bacteriol Rev. 1960 Mar;24(1):96–105. doi: 10.1128/br.24.1.96-105.1960. [DOI] [PMC free article] [PubMed] [Google Scholar]
- COLON J. I., MOULDER J. W. Folic acid in purified preparations of members of the psittacosis group of micro-organisms. J Infect Dis. 1958 Sep-Oct;103(2):109–119. doi: 10.1093/infdis/103.2.109. [DOI] [PubMed] [Google Scholar]
- FUJITA K., KOHNO S., SHISHIDO A. The incorporation of methionine into purified rickettsiae. Jpn J Med Sci Biol. 1959 Oct;12:387–390. doi: 10.7883/yoken1952.12.387. [DOI] [PubMed] [Google Scholar]
- KISLIUK R. L., SAKAMI W. A study of the mechanism of serine biosynthesis. J Biol Chem. 1955 May;214(1):47–57. [PubMed] [Google Scholar]
- KISLIUK R. L. Studies on the mechanism of formaldehyde incorporation into serine. J Biol Chem. 1957 Aug;227(2):805–814. [PubMed] [Google Scholar]
- PARETSKY D., DOWNS C. M., CONSIGLI R. A., JOYCE B. K. Studies on the physiology of rickettsiae. I. Some enzyme systems of Coxiella burnetii. J Infect Dis. 1958 Jul-Aug;103(1):6–11. doi: 10.1093/infdis/103.1.6. [DOI] [PubMed] [Google Scholar]
- WOLFE M. The quantitative determination of amino acids by paper chromatography; a solvent to replace phenol. Biochim Biophys Acta. 1957 Jan;23(1):186–191. doi: 10.1016/0006-3002(57)90302-5. [DOI] [PubMed] [Google Scholar]