Abstract
Sebek, Oldrich K. (The Upjohn Company, Kalamazoo, Mich.), Lester M. Reineke, and Durey H. Peterson. Intermediates in the metabolism of steroids by Penicillium lilacinum. J. Bacteriol. 83:1327–1331. 1962—Nonproliferating cells of Penicillium lilacinum (Thom) metabolized progesterone successively to 20-β-hydroxy-4-pregnen-3-one, testosterone, androstenedione, and testololactone. Testosterone and androstenedione were readily interconvertible. 11-α-Hydroxyprogesterone was transformed in an analogous way and its intermediate, 11-α, 20-β-dihydroxy-4-pregnen-3-one, was isolated and identified by a combination of microbiological and chemical methods.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- NESEMANN G., HUEBENER J. H., JUNK R., SCHMIDT-THOME J. [20beta-Hydroxysteroid dehydrogenase. 1. Culture of Streptomyces hydrogenans and induction of the enzyme]. Biochem Z. 1960;333:88–94. [PubMed] [Google Scholar]