Skip to main content
. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Alcohol. 2009 Dec;43(8):603–618. doi: 10.1016/j.alcohol.2009.10.006

Figure 3. Effect of chronic in vitro ethanol exposure on mIPSCs in cortical neurons.

Figure 3

Cultured neurons aged 14 days in vitro were exposed to 50 mM ethanol in the tissue culture medium for 1 to 7 days. A. Averaged mIPSCs for a control neuron and a neuron exposed to 50 mM ethanol for 24 hours. B. Percent change in average mIPSC decay time constant calculated relative to age and culture matched controls for neurons exposed to 50 mM ethanol for 1,2, or 3 days. †† p < 0.005 compared to controls by paired t-test. C. Absolute values for mIPSC decay time constants in ethanol treated neurons and controls. One day of ethanol treatment decreased mIPSC τd from 32.7±1.7 ms in control cells to 26.2±1.0 ms in ethanol treated cells. † p < 0.05 by Holm-Sidak posthoc test.