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. 2010 Jan 6;98(1):174. doi: 10.1016/j.bpj.2009.12.4277

Correction

PMCID: PMC2800972

F. Meersman, D. Bowron, A. K. Soper, and M. H. J. Koch. 2009. Counteraction of urea by trimethylamine N-oxide is due to direct interaction. Biophys J. 97:2559–2566.

Due to an error in the calculation of the nO-Hu coordination number, the second paragraph after Fig. 5 should read:

Fig. 5 illustrates that urea interacts directly (nO-Hu ≈ 0.18) with TMAO through somewhat longer OH-N hydrogen bonds (1.83 Å). It is expected that adding another equivalent of urea to the solution would largely eliminate strong direct interactions between the TMAO oxygen and water.

In Fig. 4, all numbers on the ordinate (g(r)) should be divided by 2.


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