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. 1988 Jul;85(13):4770–4774. doi: 10.1073/pnas.85.13.4770

Sources and evolution of human Alu repeated sequences.

R J Britten 1, W F Baron 1, D B Stout 1, E H Davidson 1
PMCID: PMC280517  PMID: 3387437

Abstract

Alu repeated sequences arising in DNA of the human lineage during about the last 30 million years are closely similar to a modern consensus. Alu repeats arising at earlier times share correlated blocks of differences from the current consensus at diagnostic positions in the sequence. Using these 26 positions, we can recognize four subfamilies and the older ones are each successively closer to the 7SL sequence. It appears that there has existed a series of conserved genes that are the primary sources of the Alu repeat family, presumably through retroposition. These genes have probably replaced each other in overlapping relays during the evolution of primates.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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