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. 1988 Jul;85(13):4914–4918. doi: 10.1073/pnas.85.13.4914

Retinal afferent arborization patterns, dendritic field orientations, and the segregation of function in the lateral geniculate nucleus of the monkey.

C R Michael 1
PMCID: PMC280548  PMID: 3387448

Abstract

Optic tract fibers and cell bodies in the lateral geniculate nucleus of the monkey were studied intracellularly with micropipette electrodes containing the marker enzyme horseradish peroxidase. Single optic-tract fibers always projected to only one of the six geniculate layers. The majority of the axons innervating the four parvocellular laminae were red/green opponent color units; their terminations formed cylindrical columns that were perpendicular to the layers. In similar fashion, the geniculate cells in the parvocellular layers were mostly red/green units with narrow, bipolar dendritic fields oriented normal to the laminar borders. The majority of the retinal axons ending in parvocellular layers 6 and 5 were on-center units; nearly all geniculate cells in these two laminae were also on-center neurons. In layers 4 and 3 most terminating optic-tract fibers, as well as the geniculate cells themselves, were off-center units. All axons projecting to the magnocellular layers were broad-band units with spherical terminal arborizations. The magnocellular geniculate neurons, which were also broad band, had extensive spherical dendritic fields that often crossed laminar borders. Thus, the terminal patterns of each class of retinogeniculate axon closely resembled the dendritic orientations of the functionally related geniculate target cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adams J. C. Heavy metal intensification of DAB-based HRP reaction product. J Histochem Cytochem. 1981 Jun;29(6):775–775. doi: 10.1177/29.6.7252134. [DOI] [PubMed] [Google Scholar]
  2. Adams J. C. Technical considerations on the use of horseradish peroxidase as a neuronal marker. Neuroscience. 1977;2(1):141–145. doi: 10.1016/0306-4522(77)90074-4. [DOI] [PubMed] [Google Scholar]
  3. Blakemore C., Vital-Durand F. Organization and post-natal development of the monkey's lateral geniculate nucleus. J Physiol. 1986 Nov;380:453–491. doi: 10.1113/jphysiol.1986.sp016297. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bowling D. B., Michael C. R. Projection patterns of single physiologically characterized optic tract fibres in cat. Nature. 1980 Aug 28;286(5776):899–902. doi: 10.1038/286899a0. [DOI] [PubMed] [Google Scholar]
  5. Bowling D. B., Michael C. R. Terminal patterns of single, physiologically characterized optic tract fibers in the cat's lateral geniculate nucleus. J Neurosci. 1984 Jan;4(1):198–216. doi: 10.1523/JNEUROSCI.04-01-00198.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Conley M., Penny G. R., Diamond I. T. Terminations of individual optic tract fibers in the lateral geniculate nuclei of Galago crassicaudatus and Tupaia belangeri. J Comp Neurol. 1987 Feb 1;256(1):71–87. doi: 10.1002/cne.902560107. [DOI] [PubMed] [Google Scholar]
  7. De Monasterio F. M., Gouras P. Functional properties of ganglion cells of the rhesus monkey retina. J Physiol. 1975 Sep;251(1):167–195. doi: 10.1113/jphysiol.1975.sp011086. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Derrington A. M., Krauskopf J., Lennie P. Chromatic mechanisms in lateral geniculate nucleus of macaque. J Physiol. 1984 Dec;357:241–265. doi: 10.1113/jphysiol.1984.sp015499. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Derrington A. M., Lennie P. Spatial and temporal contrast sensitivities of neurones in lateral geniculate nucleus of macaque. J Physiol. 1984 Dec;357:219–240. doi: 10.1113/jphysiol.1984.sp015498. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Dreher B., Fukada Y., Rodieck R. W. Identification, classification and anatomical segregation of cells with X-like and Y-like properties in the lateral geniculate nucleus of old-world primates. J Physiol. 1976 Jun;258(2):433–452. doi: 10.1113/jphysiol.1976.sp011429. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Friedlander M. J., Lin C. S., Stanford L. R., Sherman S. M. Morphology of functionally identified neurons in lateral geniculate nucleus of the cat. J Neurophysiol. 1981 Jul;46(1):80–129. doi: 10.1152/jn.1981.46.1.80. [DOI] [PubMed] [Google Scholar]
  12. Hickey T. L., Guillery R. W. A study of Golgi preparations from the human lateral geniculate nucleus. J Comp Neurol. 1981 Aug 20;200(4):545–577. doi: 10.1002/cne.902000407. [DOI] [PubMed] [Google Scholar]
  13. Kaplan E., Shapley R. M. X and Y cells in the lateral geniculate nucleus of macaque monkeys. J Physiol. 1982 Sep;330:125–143. doi: 10.1113/jphysiol.1982.sp014333. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Leventhal A. G., Rodieck R. W., Dreher B. Retinal ganglion cell classes in the Old World monkey: morphology and central projections. Science. 1981 Sep 4;213(4512):1139–1142. doi: 10.1126/science.7268423. [DOI] [PubMed] [Google Scholar]
  15. Perry V. H., Cowey A. Retinal ganglion cells that project to the superior colliculus and pretectum in the macaque monkey. Neuroscience. 1984 Aug;12(4):1125–1137. doi: 10.1016/0306-4522(84)90007-1. [DOI] [PubMed] [Google Scholar]
  16. Perry V. H., Oehler R., Cowey A. Retinal ganglion cells that project to the dorsal lateral geniculate nucleus in the macaque monkey. Neuroscience. 1984 Aug;12(4):1101–1123. doi: 10.1016/0306-4522(84)90006-x. [DOI] [PubMed] [Google Scholar]
  17. Saini K. D., Garey L. J. Morphology of neurons in the lateral geniculate nucleus of the monkey. A Golgi study. Exp Brain Res. 1981;42(3-4):235–248. doi: 10.1007/BF00237491. [DOI] [PubMed] [Google Scholar]
  18. Schiller P. H., Malpeli J. G. Functional specificity of lateral geniculate nucleus laminae of the rhesus monkey. J Neurophysiol. 1978 May;41(3):788–797. doi: 10.1152/jn.1978.41.3.788. [DOI] [PubMed] [Google Scholar]
  19. Sherman S. M., Wilson J. R., Kaas J. H., Webb S. V. X- and Y-cells in the dorsal lateral geniculate nucleus of the owl monkey (Aotus trivirgatus). Science. 1976 Apr 30;192(4238):475–477. doi: 10.1126/science.816006. [DOI] [PubMed] [Google Scholar]
  20. Sur M., Sherman S. M. Retinogeniculate terminations in cats: morphological differences between X and Y cell axons. Science. 1982 Oct 22;218(4570):389–389. doi: 10.1126/science.7123239. [DOI] [PubMed] [Google Scholar]
  21. Wiesel T. N., Hubel D. H. Spatial and chromatic interactions in the lateral geniculate body of the rhesus monkey. J Neurophysiol. 1966 Nov;29(6):1115–1156. doi: 10.1152/jn.1966.29.6.1115. [DOI] [PubMed] [Google Scholar]
  22. Wilson J. R., Hendrickson A. E. Neuronal and synaptic structure of the dorsal lateral geniculate nucleus in normal and monocularly deprived Macaca monkeys. J Comp Neurol. 1981 Apr 10;197(3):517–539. doi: 10.1002/cne.901970311. [DOI] [PubMed] [Google Scholar]
  23. de Courten C., Garey L. J. Morphology of the neurons in the human lateral geniculate nucleus and their normal development. A Golgi study. Exp Brain Res. 1982;47(2):159–171. doi: 10.1007/BF00239375. [DOI] [PubMed] [Google Scholar]

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