MEDICAL SCIENCES Correction for “Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice,” by Kakali Sarkar, Karen Fox-Talbot, Charles Steenbergen, Marta Bosch-Marcé, and Gregg L. Semenza, which appeared in issue 44, November 3, 2009, of Proc Natl Acad Sci USA (106:18769–18774; first published October 19, 2009; 10.1073/pnas.0910561106).
The authors note that, in Fig. 3K, the labels “AdCA5” and “AdLacZ” in the legend of the bar graph are reversed. The corrected figure and its legend appear below.
Fig. 3.
Histological analysis of ischemic adductor muscles from diabetic mice after therapy. (A–D) Hematoxylin-eosin staining of tissue sections on day 7 after femoral artery ligation and treatment with AdLacZ (A) or AdCA5 (B) (original magnification, 40×). Black arrow indicates area infiltrated with inflammatory cells and red arrow indicates area with preservation of normal muscle tissue histology. Boxed areas are shown at higher power (C and D; original magnification, 200×). (E–J) Immunohistochemical staining of infiltrated areas for macrophages (E and F), lymphocytes (G and H), and neutrophils (I and J) using F4/80, CD3 and myeloperoxidase antibodies, respectively (original magnification, 200×). (K) Quantification of infiltrated and preserved areas as percentage of total tissue area with mean ± SEM (n = 4 mice each) shown. **, P < 0.01 (Mann–Whitney test).