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. 1993 Jun;61(6):2698–2702. doi: 10.1128/iai.61.6.2698-2702.1993

A siderophore production mutant of Bordetella bronchiseptica cannot use lactoferrin as an iron source.

L A Foster 1, D W Dyer 1
PMCID: PMC280903  PMID: 8500910

Abstract

Bordetella bronchiseptica secreted a hydroxamate siderophore when grown in Fe-depleted medium. A Tn5lac insertion mutant of B. bronchiseptica, DBB22, did not produce this hydroxamate siderophore and was incapable of using lactoferrin as an Fe source. Our data suggest that B. bronchiseptica uses a siderophore for removal of Fe from lactoferrin and transferrin rather than relying upon a receptor for these host Fe-binding proteins.

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Selected References

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