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. 1993 Jul;61(7):3081–3083. doi: 10.1128/iai.61.7.3081-3083.1993

Antimicrobial activity of two bactenecins against spirochetes.

M Scocchi 1, D Romeo 1, M Cinco 1
PMCID: PMC280965  PMID: 8514417

Abstract

Bac5 and Bac7 are antimicrobial peptides of bovine neutrophils that act on enteric gram-negative bacteria. We report here that these two peptides immobilize and kill Leptospira interrogans and Leptospira biflexa with MBCs of 6 to 25 micrograms/ml. Conversely, although both peptides bind to Borrelia burgdorferi, the organism is resistant to their action.

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Selected References

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