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. 1993 Jul;61(7):3090–3092. doi: 10.1128/iai.61.7.3090-3092.1993

Amino-terminal sequence analysis of the Coccidioides immitis chitinase/immunodiffusion-complement fixation protein.

S M Johnson 1, C R Zimmermann 1, D Pappagianis 1
PMCID: PMC280967  PMID: 8514419

Abstract

A chitinase isolated from Coccidioides immitis was subjected to amino-terminal protein sequence analysis. The resulting 18-amino-acid sequence was compared with the previously reported amino acid sequence of coccidioidal immunodiffusion-complement fixation (IDCF) antigen. From the homology of the two sequences, the results support the identification of the IDCF antigen with a chitinase.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Johnson S. M., Pappagianis D. The coccidioidal complement fixation and immunodiffusion-complement fixation antigen is a chitinase. Infect Immun. 1992 Jul;60(7):2588–2592. doi: 10.1128/iai.60.7.2588-2592.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Jones J. D., Grady K. L., Suslow T. V., Bedbrook J. R. Isolation and characterization of genes encoding two chitinase enzymes from Serratia marcescens. EMBO J. 1986 Mar;5(3):467–473. doi: 10.1002/j.1460-2075.1986.tb04235.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Kaufman L., Clark M. J. Value of the concomitant use of complement fixation and immunodiffusion tests in the diagnosis of coccidioidomycosis. Appl Microbiol. 1974 Oct;28(4):641–643. doi: 10.1128/am.28.4.641-643.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Resnick S., Pappagianis D., McKerrow J. H. Proteinase production by the parasitic cycle of the pathogenic fungus Coccidioides immitis. Infect Immun. 1987 Nov;55(11):2807–2815. doi: 10.1128/iai.55.11.2807-2815.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Resnick S., Zimmer B., Pappagianis D., Eakin A., McKerrow J. Purification and amino-terminal sequence analysis of the complement-fixing and precipitin antigens from Coccidioides immitis. J Clin Microbiol. 1990 Feb;28(2):385–388. doi: 10.1128/jcm.28.2.385-388.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. SMITH C. E., SAITO M. T., BEARD R. R., KEPP R. M., CLARK R. W., EDDIE B. U. Serological tests in the diagnosis and prognosis of coccidioidomycosis. Am J Hyg. 1950 Jul;52(1):1–21. doi: 10.1093/oxfordjournals.aje.a119404. [DOI] [PubMed] [Google Scholar]
  7. SMITH C. E., SAITO M. T., SIMONS S. A. Pattern of 39,500 serologic tests in coccidioidomycosis. J Am Med Assoc. 1956 Feb 18;160(7):546–552. doi: 10.1001/jama.1956.02960420026008. [DOI] [PubMed] [Google Scholar]
  8. Watanabe T., Suzuki K., Oyanagi W., Ohnishi K., Tanaka H. Gene cloning of chitinase A1 from Bacillus circulans WL-12 revealed its evolutionary relationship to Serratia chitinase and to the type III homology units of fibronectin. J Biol Chem. 1990 Sep 15;265(26):15659–15665. [PubMed] [Google Scholar]
  9. Yuan L., Cole G. T. Isolation and characterization of an extracellular proteinase of Coccidioides immitis. Infect Immun. 1987 Sep;55(9):1970–1978. doi: 10.1128/iai.55.9.1970-1978.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Yuan L., Cole G. T., Sun S. H. Possible role of a proteinase in endosporulation of Coccidioides immitis. Infect Immun. 1988 Jun;56(6):1551–1559. doi: 10.1128/iai.56.6.1551-1559.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Zimmer B. L., Pappagianis D. Characterization of a soluble protein of Coccidiodes immitis with activity as an immunodiffusion-complement fixation antigen. J Clin Microbiol. 1988 Nov;26(11):2250–2256. doi: 10.1128/jcm.26.11.2250-2256.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]

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