Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1993 Aug;61(8):3527–3529. doi: 10.1128/iai.61.8.3527-3529.1993

Immune recognition of polar pili from Pseudomonas aeruginosa O.

W Smart 1, P A Sastry 1, W Paranchych 1, B Singh 1
PMCID: PMC281032  PMID: 8101509

Abstract

The B- and T-cell antigenic sites on type O pili from Pseudomonas aeruginosa were determined by using an antipilus antibody competition assay and PAO-immune T-cell blasts in proliferation studies. The citraconylated tryptic digest III region (residues 54 to 120) was determined to be an immunodominant site for both T and B cells on the pilin molecule.

Full text

PDF
3527

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Frost L. S., Paranchych W. Composition and molecular weight of pili purified from Pseudomonas aeruginosa K. J Bacteriol. 1977 Jul;131(1):259–269. doi: 10.1128/jb.131.1.259-269.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Lee K. K., Paranchych W., Hodges R. S. Cross-reactive and strain-specific antipeptide antibodies to Pseudomonas aeruginosa PAK and PAO pili. Infect Immun. 1990 Sep;58(9):2727–2732. doi: 10.1128/iai.58.9.2727-2732.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Paranchych W., Sastry P. A., Frost L. S., Carpenter M., Armstrong G. D., Watts T. H. Biochemical studies on pili isolated from Pseudomonas aeruginosa strain PAO. Can J Microbiol. 1979 Oct;25(10):1175–1181. doi: 10.1139/m79-182. [DOI] [PubMed] [Google Scholar]
  4. Sastry P. A., Pearlstone J. R., Smillie L. B., Paranchych W. Studies on the primary structure and antigenic determinants of pilin isolated from Pseudomonas aeruginosa K. Can J Biochem Cell Biol. 1985 Apr;63(4):284–291. doi: 10.1139/o85-042. [DOI] [PubMed] [Google Scholar]
  5. Smart W., Sastry P. A., Paranchych W., Singh B. Mapping of the T-cell recognition sites of Pseudomonas aeruginosa PAK polar pili. Infect Immun. 1988 Jan;56(1):18–23. doi: 10.1128/iai.56.1.18-23.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Watts T. H., Sastry P. A., Hodges R. S., Paranchych W. Mapping of the antigenic determinants of Pseudomonas aeruginosa PAK polar pili. Infect Immun. 1983 Oct;42(1):113–121. doi: 10.1128/iai.42.1.113-121.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Weiss R. L. The structure and occurrence of pili (fimbriae) on Pseudomonas aeruginosa. J Gen Microbiol. 1971 Aug;67(2):135–143. doi: 10.1099/00221287-67-2-135. [DOI] [PubMed] [Google Scholar]
  8. Woods D. E., Straus D. C., Johanson W. G., Jr, Berry V. K., Bass J. A. Role of pili in adherence of Pseudomonas aeruginosa to mammalian buccal epithelial cells. Infect Immun. 1980 Sep;29(3):1146–1151. doi: 10.1128/iai.29.3.1146-1151.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES