Table 2.

Association between CHQ Physical Functioning Summary Score and Echocardiography^*

	Univariable		Multivariable**
Variable	PE	p	PE	p	Reliability***
Overall AV valve regurgitation		0.27
None	reference
Mild	1.214
Moderate or severe	−1.448
Semilunar valve regurgitation		0.77
None	reference
Mild	0.615
Moderate	1.910
End-systolic volume Z score	−0.718	0.005	−0.689	0.007	43%
End-diastolic volume Z score	−0.810	0.02
Total stroke volume Z score	−0.488	0.16
Total ejection fraction Z score	0.423	0.17
Total ventricular mass Z score	−0.700	0.02
Total mass:end-diastolic volume ratio	0.225	0.89
Tei index	−7.160	0.08	−6.422	0.10	48%
dP/dt (mm Hg/sec)	0.000	0.63
AVV peak late diastolic velocity (m/sec)	−11.02	<0.05
Early:late AVV diastolic velocity (E/A)	1.580	0.23
Duration of AVV late diastolic inflow (msec)	−0.026	0.33
Absolute systemic ventricular flow propagation rate (cm/sec)	0.040	0.40
Ratio of AV to tissue Doppler early diastolic flow velocity	−0.158	0.41
Tissue Doppler peak early diastolic flow velocity (cm/sec)	−0.122	0.56

PE, parameter estimate

Parameter estimates represent the degree of change in the Summary Score associated with a one integer unit change in the laboratory testing variable.

^*Analysis limited to 389 subjects. Of those with a current pacemaker, none were being paced in a VVI mode. Missing values were not imputed for univariable analyses, and were imputed for multivariable analyses.

^**R²=0.03 (R² adjusted=0.02), p=0.005

^***From bootstrap bagging (presented for the variables included in the multivariable model)