Effect of capsaicin treatment on mechanosensitivity of afferents one day after plantar incision. A: Sample recording traces showing responses to mechanical stimuli. Both C- and Aδ-fibers from either capsaicin or vehicle treatment groups have force-related increase responses to the ascending series of mechanical stimuli (40, 80, and 120 mN). CV = conduction velocity. B and C: The percentage mechanosensitivity at each force (B) and stimulus-response function (C) of C-fibers in capsaicin (n = 38, ○) vs. vehicle group (n = 39, ●). D and E: The percentage of mechanosensitivity (D) and stimulus-response function (E) of Aδ-fibers in capsaicin (n = 29, ○) vs. vehicle group (n = 22, ●).