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. 2009 Dec 23;151(2):793–801. doi: 10.1210/en.2009-0976

Figure 5.

Figure 5

Cre recombinase expression is regulated by TH. A, ISH for TRH mRNA using a digoxigenin-labeled probe in WT and F40: TRH-Cre mice under euthyroid, hypothyroid, and hyperthyroid conditions. For the PVH: magnification, ×10; scale bar, 100 μm. B, IHC staining was performed for Cre on hypothyroid WT and euthyroid, hypothyroid, and hyperthyroid F40: TRH-Cre mice. The PVH of each genetic background is shown under different thyroid conditions (n = 3). In the fourth column, images of the amygdala are representative of each thyroid condition and genetic background. Images of the PVH and the amygdala: magnification, ×10; scale bar per region, 100 μm.