Table 1.
Classification of disorders of ovulation
| Group | Description | Site of the lesion | Hormone concentration |
|---|---|---|---|
| WHO | Hypogonadotrophic | Central | Low FSH |
| type I | Hypo-estrogenic | Low estradiol | |
| Normoprolactinemic | Normal prolactin | ||
| WHO | Hypogonadotrophic | Hypothalamic-pituitary | Normal FSH |
| type II | Normo-estrogenic | ovarian axis | Normal estradiol |
| Normoprolactinemic | Normal prolactin | ||
| WHO | Hypergonadotrophic | Ovarian failure | High FSH |
| type III | Hypo-estrogenic | Low estradiol | |
| Normoprolactinemic | Normal prolactin | ||
| Hyperprolactinemic | Hyperprolactinemic | Central | Normal FSH |
| Normal estradiol | |||
| High prolactin |
Adapted with permission from Shetty A. Disorders of ovulation. In: Templeton AA. ed. Management of Infertility for the MRCOG and Beyond. London: RCOG press; 2001.161 Copyright © 2001 RCOG Press.
Abbreviation: FSH, follicle stimulating hormone.