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. Author manuscript; available in PMC: 2011 Feb 17.
Published in final edited form as: Vaccine. 2009 Dec 10;28(7):1870. doi: 10.1016/j.vaccine.2009.11.076

Fig. 3.

Fig. 3

Removal of the BA5 epitope from rLcrV does not abolish its protective antigen attributes. 8 week old BALB/c mice were vaccinated with 50 µg of recombinant LcrV or its variant lacking residues 196 to 225 (rLcrVΔ196–225), adsorbed to 25% Alhydrogel, on day 0 and 21. At day 42 mice were challenged by subcutaneous injection with Y. pestis CO92, using 20 MLD (white symbols) or 1,000 MLD (black symbols). Mice were monitored over 14 days for survival.