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. 1988 Dec;85(24):9674–9678. doi: 10.1073/pnas.85.24.9674

Some mismatch repair activities in Escherichia coli.

J P Radicella 1, E A Clark 1, M S Fox 1
PMCID: PMC282834  PMID: 2974159

Abstract

Heterozygous bacteriophage lambda DNA molecules, whose replication requires mismatch correction of a mutant nucleotide in the transcribed strand, provide an assay for localized mismatch repair in Escherichia coli. We describe two systems: one removes the A in C.A or G.A mismatches and the other removes one or the other C in a C.C mismatch. Mutations disabling the first system result in a mutator phenotype that may be identical to mutY.

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Selected References

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