Erratum to: AGE DOI 10.1007/s11357-006-9018-4
We recently discovered an error in our manuscript “Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet” (Age. 2007 Mar; 29(1):29–39). The amino acid content of the chemically defined diet that we used (Harlan Teklad Diet TD.04310) was 10-fold lower than our intended specifications, which we had designed to resemble the amino acid content in conventional media (Table 1). The error means that the defined media we used was essentially amino-acid restricted, which could explain the unusual longevity of the flies in our study (Flatt 2009; Mair et al. 2005; Min and Tatar 2006). Work is underway by other groups to examine this possibility.
Table 1.
Amino Acids | Actual g / L | Actual % | Intended % |
---|---|---|---|
L-Aspartic Acid | 2.5 g | 0.025% | 0.25% |
L-Glutamic Acid | 5.6 g | 0.056% | 0.56% |
L-Serine | 2.3 g | 0.023% | 0.23% |
Glycine | 1.0 g | 0.010% | 0.10% |
L-Histidine HCl-H2O | 1.1 g | 0.011% | 0.11% |
L-Arginine HCl | 3.9 g | 0.039% | 0.39% |
L-Threonine | 2.1 g | 0.021% | 0.21% |
L-Alanine | 2.6 g | 0.026% | 0.26% |
L-Proline | 2.1 g | 0.021% | 0.21% |
L-Tyrosine | 1.9 g | 0.019% | 0.19% |
L-Valine | 3.0 g | 0.030% | 0.30% |
L-Cystine | 1.0 g | 0.010% | 0.10% |
L-Isoleucine | 1.9 g | 0.019% | 0.19% |
L-Leucine | 3.1 g | 0.031% | 0.31% |
L-Phenylalanine | 2.2 g | 0.022% | 0.22% |
L-Lysine HCl | 6.5 g | 0.065% | 0.65% |
L-Tryptophan | 17.4 g | 0.175% | 1.75% |
Footnotes
The online version of the original article can be found at 10.1007/s11357-006-9018-4.
References
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