Abstract
The responses of Purkinje cells in the cerebellum produced by various positions of the limbs were studied in decerebrated unanesthetized cats. The majority of units located in the intermediate zone of the anterior lobe selectively reacted to definite postures of the limbs: some of them were active when a given limb was in an extended position and were silent when it was in flexion; the other ones, on the contrary, were active when the limb was flexed and silent when it was extended. The rate of discharges was in both cases the same and amounted to 40 to 80 per second. It did not change with the lapse of time, and remained the same when flaxedil was administered. These results, in connection with some other data, seem to explain the problem of how the cerebellum transforms the information about the tensions of tendons and muscles, delivered by the tendon organs and muscle spindles, respectively, into the information about movements.
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Selected References
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- BROOKHART J. M., MORUZZI G., SNIDER R. S. Spike discharges of single units in the cerebellar cortex. J Neurophysiol. 1950 Nov;13(6):465–486. doi: 10.1152/jn.1950.13.6.465. [DOI] [PubMed] [Google Scholar]
- COMBS C. M. Electro-anatomical study of cerebellar localization; stimulation of various afferents. J Neurophysiol. 1954 Mar;17(2):123–143. doi: 10.1152/jn.1954.17.2.123. [DOI] [PubMed] [Google Scholar]
- GRANIT R., PHILLIPS C. G. Excitatory and inhibitory processes acting upon individual Purkinje cells of the cerebellum in cats. J Physiol. 1956 Sep 27;133(3):520–547. doi: 10.1113/jphysiol.1956.sp005606. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Matthews B. H. Nerve endings in mammalian muscle. J Physiol. 1933 Apr 13;78(1):1–53. doi: 10.1113/jphysiol.1933.sp002984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Oscarsson O., Rosén I. Short-latency projections to the cat's cerebral cortex from skin and muscle afferents in the contralateral forelimb. J Physiol. 1966 Jan;182(1):164–184. doi: 10.1113/jphysiol.1966.sp007816. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Thach W. T., Jr Somatosensory receptive fields of single units in cat cerebellar cortex. J Neurophysiol. 1967 Jul;30(4):675–696. doi: 10.1152/jn.1967.30.4.675. [DOI] [PubMed] [Google Scholar]
- Thomas R. C., Wilson V. J. Precise localization of Renshaw cells with a new marking technique. Nature. 1965 Apr 10;206(980):211–213. doi: 10.1038/206211b0. [DOI] [PubMed] [Google Scholar]