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. 1970 Jun;66(2):425–432. doi: 10.1073/pnas.66.2.425

Synthesis of Immunoglobulin Heavy and Light Chains by the Free Ribosomes of a Mouse Plasma Cell Tumor*

B Lisowska-Bernstein 1,2, M E Lamm 1,2,, P Vassalli 1,2
PMCID: PMC283062  PMID: 4194867

Abstract

Free and membrane-bound ribosomes have been isolated from a mouse plasma cell tumor secreting immunoglobulins, and allowed to synthesize proteins under cell-free conditions. Analysis of the products of synthesis by autoradiography of immunoelectrophoresis and peptide maps indicates that both types of ribosomes synthesize heavy and light immunoglobulin chains.

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Selected References

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