Skip to main content
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1970 Jul;66(3):765–772. doi: 10.1073/pnas.66.3.765

Patterned Neural Activity of a Mutant Drosophila melanogaster*

Kazuo Ikeda 1,2,, William D Kaplan 1,2
PMCID: PMC283116  PMID: 5269239

Abstract

Hyperkinetic 1P, a behavioral mutant of Drosophila melanogaster, shows rhythmic leg-shaking action derived from mutation of a single, sex-linked gene. The neural mechanism governing this abnormal motor function consists of rhythmic bursts of activity produced by motor neurons located within the thoracic ganglion. The mechanism of the pattern formation was independent both of sensory information and higher centers in the central nervous system but endogenous within the ganglion. Two types of neurons which appear to be involved in the pattern formation were found within six limited regions.

Full text

PDF
765

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benzer S. BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION. Proc Natl Acad Sci U S A. 1967 Sep;58(3):1112–1119. doi: 10.1073/pnas.58.3.1112. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Callec J. J., Boistel J. Etude de divers types d'activités électriques enregistrées par microélectrodes capillaires au niveau du dernier ganglion abdominal de la blatte, Periplaneta americana L. C R Seances Soc Biol Fil. 1966;160(10):1943–1947. [PubMed] [Google Scholar]
  3. HAGIWARA S., WATANABE A. Discharges in motoneurons of cicada. J Cell Physiol. 1956 Jun;47(3):415–428. doi: 10.1002/jcp.1030470308. [DOI] [PubMed] [Google Scholar]
  4. Hotta Y., Benzer S. Abnormal electroretinograms in visual mutants of Drosophila. Nature. 1969 Apr 26;222(5191):354–356. doi: 10.1038/222354a0. [DOI] [PubMed] [Google Scholar]
  5. Ikeda K., Boettiger E. G. Studies on the flight mechanism of insects. II. The innervation and electrical activity of the fibrillar muscles of the bumble bee, Bombus. J Insect Physiol. 1965 Jun;11(6):779–789. doi: 10.1016/0022-1910(65)90157-5. [DOI] [PubMed] [Google Scholar]
  6. Kaplan W. D., Trout W. E., 3rd The behavior of four neurological mutants of Drosophila. Genetics. 1969 Feb;61(2):399–409. doi: 10.1093/genetics/61.2.399. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Kerkut G. A., Pitman R. M., Walker R. J. Iontophoretic application of acetylcholine and GABA onto insect central neurones. Comp Biochem Physiol. 1969 Nov 15;31(4):611–633. doi: 10.1016/0010-406x(69)90063-2. [DOI] [PubMed] [Google Scholar]
  8. Kerkut G. A., Pitman R. M., Walker R. J. Sensitivity of neurones of the insect central nervous system to iontophoretically applied acetylcholine or GABA. Nature. 1969 Jun 14;222(5198):1075–1076. doi: 10.1038/2221075b0. [DOI] [PubMed] [Google Scholar]
  9. Pak W. L., Grossfield J., White N. V. Nonphototactic mutants in a study of vision of Drosophila. Nature. 1969 Apr 26;222(5191):351–354. doi: 10.1038/222351a0. [DOI] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES