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. 1970 Oct;67(2):799–806. doi: 10.1073/pnas.67.2.799

Kinetic Model of Conduction Changes across Excitable Membranes*

Mahendra K Jain 1, Richard H L Marks 1, E H Cordes 1
PMCID: PMC283276  PMID: 5289023

Abstract

A kinetic model describing conduction changes across excitable membranes is proposed. It assumes that a population of discrete membrane sites is distributed among several distinct functional states determined by the voltage across the membrane. Interconversion of these states is postulated to occur by first-order reactions. It provides a satisfactory description of the central aspects of excitable membrane behavior, including current-time and current-voltage relationships, action potential, and effects of inhibitors.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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