Abstract
Phonoangiography, the quantitative analysis of sounds produced by blood flow, has been used to investigate local fluid motion in arteries narrowed by atherosclerosis. The sound spectra measured in vivo were found to be identical to those obtained in laboratory investigations of turbulent pipe flow. A theoretical model is proposed which: (a) quantitatively relates the in vivo and in vitro data, and (b) allows estimation of the clinically important parameters of arterial diameter, flow velocity, local turbulence intensity, and wall pressure fluctuations. The results of calculations using data from human subjects agree with known arterial diameters and blood flow velocities.
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Selected References
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- BARNETT G. O., GREENFIELD J. C., Jr, FOX S. M., 3rd The technique of estimating the instantaneous aortic blood velocity in man from the pressure gradient. Am Heart J. 1961 Sep;62:359–366. doi: 10.1016/0002-8703(61)90402-1. [DOI] [PubMed] [Google Scholar]
- Cramér K., Paulin S., Werkö L. Coronary angiographic findings in correlation with age, body weight, blood pressure, serum lipids, and smoking habits. Circulation. 1966 Jun;33(6):888–900. doi: 10.1161/01.cir.33.6.888. [DOI] [PubMed] [Google Scholar]
- Fredrickson D. S., Levy R. I., Lees R. S. Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. N Engl J Med. 1967 Jan 5;276(1):34–contd. doi: 10.1056/NEJM196701052760107. [DOI] [PubMed] [Google Scholar]
- Proudfit W. L., Shirey E. K., Sones F. M., Jr Selective cine coronary arteriography. Correlation with clinical findings in 1,000 patients. Circulation. 1966 Jun;33(6):901–910. doi: 10.1161/01.cir.33.6.901. [DOI] [PubMed] [Google Scholar]
- Robbins S. L., Bentov I. The kinetics of viscous flow in a model vessel. Effect of stenoses of varying size, shape, and length. Lab Invest. 1967 Jun;16(6):864–874. [PubMed] [Google Scholar]
- Strandness D. E., Jr, Schultz R. D., Sumner D. S., Rushmer R. F. Ultrasonic flow detection. A useful technic in the evaluation of peripheral vascular disease. Am J Surg. 1967 Mar;113(3):311–320. doi: 10.1016/0002-9610(67)90272-3. [DOI] [PubMed] [Google Scholar]
- Turpeinen O., Miettinen M., Karvonen M. J., Roine P., Pekkarinen M., Lehtosuo E. J., Alivirta P. Dietary prevention of coronary heart disease: long-term experiment. I. Observations on male subjects. Am J Clin Nutr. 1968 Apr;21(4):255–276. doi: 10.1093/ajcn/21.4.255. [DOI] [PubMed] [Google Scholar]
