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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1970 Oct;67(2):961–967. doi: 10.1073/pnas.67.2.961

Two Radiation-Induced Chromosomal Inversions in Mice (Mus musculus)

Thomas H Roderick 1, Norman L Hawes 1
PMCID: PMC283299  PMID: 5289032

Abstract

Whole-body x-irradiation of male mice has produced presumptive paracentric inversions in 15 animals, as evidenced by high frequencies of first meiotic anaphase bridges. Two of the highest frequencies observed have been propagated through several generations and found to behave as dominant genes. Acentric fragments were observed associated with about 10% of the bridges. The first inversion, in linkage group XIII, has been designated In(13)1Rk, and the second, in linkage group XVII, In(17)2Rk. For In(13)1Rk, recombination was reduced between loci inside and outside the inverted segment.

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Selected References

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  1. EVANS E. P., BRECKON G., FORD C. E. AN AIR-DRYING METHOD FOR MEIOTIC PREPARATIONS FROM MAMMALIAN TESTES. Cytogenetics. 1964;3:289–294. doi: 10.1159/000129818. [DOI] [PubMed] [Google Scholar]
  2. FORD C. E., HAMERTON J. L. A colchicine, hypotonic citrate, squash sequence for mammalian chromosomes. Stain Technol. 1956 Nov;31(6):247–251. doi: 10.3109/10520295609113814. [DOI] [PubMed] [Google Scholar]

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