Skip to main content
NCBI home page
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1970 Dec;67(4):1722–1726. doi: 10.1073/pnas.67.4.1722

Mutation and Recombination of Bacteriophage Lambda: Effect of Ultraviolet Radiation*

Akiko Miura 1,2,†, Jun-ichi Tomizawa 1,2
PMCID: PMC283418  PMID: 5276152

Abstract

Defects in the bacterial recB or recC or phage red or int gene did not impair ultraviolet light-induced clear mutations of λ phage. Clear mutants of cI and cII genes were not enriched among RecA-promoted UV-induced recombinants between the N and O genes which closely encompass the c genes. No correlation was observed between UV-induced mutation and genetic recombination.

Full text

PDF
1722

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Appleyard R K. Segregation of Lambda Lysogenicity during Bacterial Recombination in Escherichia Coli K12. Genetics. 1954 Jul;39(4):429–439. doi: 10.1093/genetics/39.4.429. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CAMPBELL A. Sensitive mutants of bacteriophage lambda. Virology. 1961 May;14:22–32. doi: 10.1016/0042-6822(61)90128-3. [DOI] [PubMed] [Google Scholar]
  3. DEMEREC M. SELFER MUTANTS OF SALMONELLA TYPHIMURIUM. Genetics. 1963 Nov;48:1519–1531. doi: 10.1093/genetics/48.11.1519. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Demerec M. "SELFERS"-ATTRIBUTED TO UNEQUAL CROSSOVERS IN SALMONELLA. Proc Natl Acad Sci U S A. 1962 Oct;48(10):1696–1704. doi: 10.1073/pnas.48.10.1696. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Echolas H., Gingery R. Mutants of bacteriophage lambda defective in vegetative genetic recombination. J Mol Biol. 1968 Jul 14;34(2):239–249. doi: 10.1016/0022-2836(68)90249-0. [DOI] [PubMed] [Google Scholar]
  6. Emmerson P. T. Recombination deficient mutants of Escherichia coli K12 that map between thy A and argA. Genetics. 1968 Sep;60(1):19–30. doi: 10.1093/genetics/60.1.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Howard-Flanders P., Theriot L. Mutants of Escherichia coli K-12 defective in DNA repair and in genetic recombination. Genetics. 1966 Jun;53(6):1137–1150. doi: 10.1093/genetics/53.6.1137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. KAISER A. D. Mutations in a temperate bacteriophage affecting its ability to lysogenize Escherichia coli. Virology. 1957 Feb;3(1):42–61. doi: 10.1016/0042-6822(57)90022-3. [DOI] [PubMed] [Google Scholar]
  9. MAGNI G. E. THE ORIGIN OF SPONTANEOUS MUTATIONS DURING MEIOSIS. Proc Natl Acad Sci U S A. 1963 Nov;50:975–980. doi: 10.1073/pnas.50.5.975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Manly K. F., Signer E. R., Radding C. M. Nonessential functions of bacteriophage lambda. Virology. 1969 Feb;37(2):177–188. doi: 10.1016/0042-6822(69)90197-4. [DOI] [PubMed] [Google Scholar]
  11. Miura A., Tomizawa J. I. Studies on radiation-sensitive mutants of E. coli. 3. Participation of the rec system in induction of mutation by ultraviolet irradiation. Mol Gen Genet. 1968;103(1):1–10. doi: 10.1007/BF00271151. [DOI] [PubMed] [Google Scholar]
  12. Ogawa H., Shimada K., Tomizawa J. Studies on radiation-sensitive mutants of E. coli. I. Mutants defective in the repair synthesis. Mol Gen Genet. 1968 May 3;101(3):227–244. doi: 10.1007/BF00271625. [DOI] [PubMed] [Google Scholar]
  13. Sesnowitz-Horn S., Adelberg E. A. Proflavin treatment of Escherichia coli: generation of frameshift mutations. Cold Spring Harb Symp Quant Biol. 1968;33:393–402. doi: 10.1101/sqb.1968.033.01.045. [DOI] [PubMed] [Google Scholar]
  14. Signer E. R., Weil J. Recombination in bacteriophage lambda. I. Mutants deficient in general recombination. J Mol Biol. 1968 Jul 14;34(2):261–271. doi: 10.1016/0022-2836(68)90251-9. [DOI] [PubMed] [Google Scholar]
  15. Witkin E. M. The mutability toward ultraviolet light of recombination-deficient strains of Escherichia coli. Mutat Res. 1969 Jul-Aug;8(1):9–14. doi: 10.1016/0027-5107(69)90135-3. [DOI] [PubMed] [Google Scholar]
  16. Yoshikawa H. Mutations Resulting from the Transformation of BACILLUS SUBTILIS. Genetics. 1966 Nov;54(5):1201–1214. doi: 10.1093/genetics/54.5.1201. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES