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. 1970 Dec;67(4):1914–1917. doi: 10.1073/pnas.67.4.1914

Leukemia Virus Activation in Chronic Allogeneic Disease

M S Hirsch *,*, P H Black *,*, G S Tracy *,*, S Leibowitz †, R S Schwartz †
PMCID: PMC283447  PMID: 4395204

Abstract

Young adult (BALB/c × A/J)F1 hybrid mice have no detectable leukemia viruses. When inoculated with parental BALB/c spleen lymphoid cells, also free of detectable virus, leukemia viruses rapidly become activated in the injected host. Because of similarities between such graft-induced allogeneic disease and spontaneous autoimmunity, it is proposed that autoimmune reactions may activate latent viruses.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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