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. 1970 Dec;67(4):1967–1974. doi: 10.1073/pnas.67.4.1967

Glycyl-tRNA Synthetase: An Oligomeric Protein Containing Dissimilar Subunits*

Dennis L Ostrem 1,†, Paul Berg 1
PMCID: PMC283454  PMID: 4923123

Abstract

Glycyl-tRNA synthetase from Escherichia coli is a tetramer containing two small (33,000 daltons) and two large (80,000 daltons) subunits. The subunits can be separated and then reassembled to form active enzyme. Genetically altered glycyl-tRNA synthetases are modified in either the large or the small subunit. Wild type activity can be reconstituted in vitro by mixing extracts containing enzymes with modifications in different subunits.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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