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. 1987 Jul;61(7):2339–2343. doi: 10.1128/jvi.61.7.2339-2343.1987

Insertion and truncation of c-myb by murine leukemia virus in a myeloid cell line derived from cultures of normal hematopoietic cells.

Y Weinstein, J L Cleveland, D S Askew, U R Rapp, J N Ihle
PMCID: PMC283705  PMID: 2884332

Abstract

A retroviral insertion into the c-myb gene, which resulted in a 3' truncation, was found in an in vitro-derived myeloid cell line. The retroviral insertion occurred at precisely the same nucleotide at which another murine leukemia virus insertion occurred in an in vivo-induced myeloid leukemia. These findings suggest that comparable events may be required for the derivation of myeloid cell lines in vitro and for induction of myeloid leukemia in vivo.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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