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. 1980 Mar;17(3):516–517. doi: 10.1128/aac.17.3.516

In vitro activities of cefotaxime and moxalactam (LY127935) against Haemophilus influenzae.

J H Jorgensen, S A Crawford, G A Alexander
PMCID: PMC283820  PMID: 6252832

Abstract

The in vitro activities of two new beta-lactam antibiotics, cefotaxime and moxalactam (LY127935), were compared with those of cefamandole, cefoxitin, cefuroxime, and ampicillin against both beta-lactamase-producing and non-beta-lactamase-producing isolates of Haemophilus influenzae. Both cefotaxime and LY127935 were highly active against all isolates irrespective of beta-lactamase production.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Jorgensen J. H., Alexander G. A. Comparative activities of selected beta-lactam antibiotics against Haemophilus influenzae. Antimicrob Agents Chemother. 1978 Feb;13(2):342–343. doi: 10.1128/aac.13.2.342. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Jorgensen J. H., Lee J. C., Alexander G. A. Rapid penicillinase paper strip test for detection of beta-lactamase-producing Haemophilus influenzae and Neisseria gonorrhoeae. Antimicrob Agents Chemother. 1977 Jun;11(6):1087–1088. doi: 10.1128/aac.11.6.1087. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Khan W., Ross S., Rodriguez W., Controni G., Saz A. K. Haemophilus influenzae type B resistant to ampicillin. A report of two cases. JAMA. 1974 Jul 15;229(3):298–301. [PubMed] [Google Scholar]
  4. Manten A., van Klingeren B., Dessens-Kroon M. Chloramphenicol resistance in Haemophilus influenzae. Lancet. 1976 Mar 27;1(7961):702–702. doi: 10.1016/s0140-6736(76)92832-4. [DOI] [PubMed] [Google Scholar]
  5. Rahal J. J., Jr, Simberkoff M. S. Bactericidal and bacteriostatic action of chloramphenicol against memingeal pathogens. Antimicrob Agents Chemother. 1979 Jul;16(1):13–18. doi: 10.1128/aac.16.1.13. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Sosna J. P., Murray P. R., Medoff G. Comparison of the in vitro activities of HR756 with cephalothin, cefoxitin, and cefamandole. Antimicrob Agents Chemother. 1978 Dec;14(6):876–879. doi: 10.1128/aac.14.6.876. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Tomeh M. O., Starr S. E., McGowan J. E., Jr, Terry P. M., Nahmias A. J. Ampicillin-resistant Haemophilus influenzae type B infection. JAMA. 1974 Jul 15;229(3):295–297. [PubMed] [Google Scholar]
  8. Van Landuyt H. W., Pyckavet M. In vitro of cefotaxime against cephalothin-resistant clinical isolates. Antimicrob Agents Chemother. 1979 Jul;16(1):109–111. doi: 10.1128/aac.16.1.109. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Ward J. I., Tsai T. F., Filice G. A., Fraser D. W. Prevalence of ampicillin- and chloramphenicol-resistant strains of Haemophilus influenzae causing meningitis and bacteremia: national survey of hospital laboratories. J Infect Dis. 1978 Sep;138(3):421–424. doi: 10.1093/infdis/138.3.421. [DOI] [PubMed] [Google Scholar]
  10. Wise R., Rollason T., Logan M., Andrews J. M., Bedford K. A. HR 756, a highly active cephalosporin: comparison with cefazolin and carbenicillin. Antimicrob Agents Chemother. 1978 Dec;14(6):807–811. doi: 10.1128/aac.14.6.807. [DOI] [PMC free article] [PubMed] [Google Scholar]

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