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. 1980 Apr;17(4):743–749. doi: 10.1128/aac.17.4.743

Cefoperazone (T-1551), a new semisynthetic cephalosporin: comparison with cephalothin and gentamicin.

R N Jones, P C Fuchs, A L Barry, T L Gavan, H M Sommers, E H Gerlach
PMCID: PMC283865  PMID: 6446879

Abstract

The in vitro activity of cefoperazone (T-1551) against almost 9,000 recent clinical isolates at six institutions was tested and compared with that of cephalothin and gentamicin. The modal minimum inhibitory concentrations of cefoperazone were 16- and 4-fold less than those of cephalothin and gentamicin, respectively, against 5,503 strains of Enterobacteriaceae. Species normally resistant to cephalothin, such as indole-positive protease and enterobacters, were almost universally susceptible to cefoperazone. Cefoperazone demonstrated activity comparable to gentamicin against Pseudomonas aeruginosa and other pseudomonads.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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