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. 1980 Jun;17(6):965–968. doi: 10.1128/aac.17.6.965

Defective killing of enterococci: a common property of antimicrobial agents acting on the cell wall.

D J Krogstad, A R Pargwette
PMCID: PMC283912  PMID: 6902640

Abstract

We tested the ability of antimicrobial agents that act on the cell wall to kill enterococci and found defective killing (a minimal bactericidal concentration/minimal inhibitory concentration ratio of greater than or equal to 32) with both beta-lactams (penicillin G and cephalothin) and non-beta-lactams (vancomycin, cycloserine, and bacitracin). Our results indicate that the resistance of enterococci to antimicrobial killing spans the spectrum of agents known to inhibit cell wall synthesis and suggest that the mechanism responsible for enterococcal resistance to killing by these drugs may be a defective autolytic enzyme system.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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