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. 1980 Aug;18(2):357–359. doi: 10.1128/aac.18.2.357

Effects of antituberculosis and antileprosy drugs on mycobacteriophage D29 growth.

H L David, S Clavel, F Clement, J Moniz-Pereira
PMCID: PMC283997  PMID: 7447413

Abstract

The minimal inhibitory concentrations of antituberculosis and antileprosy drugs were determined for Mycobacterium aurum. The concentrations that reduced the final yield of bacteriophage D29R1 by 50% and the time during the replication cycle at which the drugs completely inhibited phage production were estimated. THe 50% inhibitory concentration/minimal inhibitory concentration ratios were close to 1.0 for clofazimine, colistin, rifampin, and streptomycin; these ratios were high for dapsone (diaminodiphenylsulfone) and isoniazid. Ethambutol (minimal inhibitory concentration, 1.0 micrograms/ml) was without effect on viral growth.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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