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. 1980 Sep;18(3):480–482. doi: 10.1128/aac.18.3.480

pJT2: unusual H1 plasmid in a highly virulent lactose-positive and chloramphenicol-resistant Salmonella typhimurium strain from calves.

J F Timoney, D E Taylor, S Shin, P McDonough
PMCID: PMC284027  PMID: 6999986

Abstract

A lactose-positive and chloramphenicol-resistant strain of Salmonella typhimurium of high virulence was isolated from an outbreak of enteric and septicemic salmonellosis in veal calves. the lactose-positive marker was located on an H1 plasmid, pJT2, together with resistance to chloramphenicol, streptomycin, sulfonamides, and tetracycline, pJT2 was unusually large and had a molecular weight of about 150 X 10(6). A similar plasmid was also present in a third of the Escherichia coli strains isolated from the intestines of septicemic calves during the outbreak. Spontaneously derived Lac- derivatives of pJT2 had an approximate molecular weight of 140 X 10(6).

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Selected References

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