Abstract
The in vitro bactericidal interactions of penicillin G, cefotaxime, or vancomycin in combination with gentamicin were compared against 20 group G streptococci by the timed kill curve method. Synergy was noted at the following frequencies: penicillin plus gentamicin, 80%; cefotaxime plus gentamicin, 85%; vancomycin plus gentamicin, 90%. There was no bactericidal antagonism observed.
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Selected References
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- Bayer A. S., Lam K. In vitro susceptibility of group G streptococci to ten antimicrobial agents with broad gram-positive spectra. Clin Ther. 1983;5(4):391–397. [PubMed] [Google Scholar]
- Bouza E., Meyer R. D., Busch D. F. Group G streptococcal endocarditis. Am J Clin Pathol. 1978 Jul;70(1):108–111. doi: 10.1093/ajcp/70.1.108. [DOI] [PubMed] [Google Scholar]
- Durack D. T., Beeson P. B. Experimental bacterial endocarditis. I. Colonization of a sterile vegetation. Br J Exp Pathol. 1972 Feb;53(1):44–49. [PMC free article] [PubMed] [Google Scholar]
- Fujita N. K., Lam K., Bayer A. S. Septic arthritis due to group G streptococcus. JAMA. 1982 Feb 12;247(6):812–813. [PubMed] [Google Scholar]
- Lam K., Bayer A. S. Serious infections due to group G streptoccocci. Report of 15 cases with in vitro-in vivo correlations. Am J Med. 1983 Oct;75(4):561–570. doi: 10.1016/0002-9343(83)90434-5. [DOI] [PubMed] [Google Scholar]
- Lin A. N., Karasik A., Salit I. E., Fam A. G. Group G streptococcal arthritis. J Rheumatol. 1982 May-Jun;9(3):424–427. [PubMed] [Google Scholar]
- Moellering R. C., Jr Antimicrobial synergism--an elusive concept. J Infect Dis. 1979 Oct;140(4):639–641. doi: 10.1093/infdis/140.4.639. [DOI] [PubMed] [Google Scholar]
- Nagel D. A., Albright J. A., Hollingsworth J. W. Studies on the pathophysiology and some host defense factors in staphylococcal arthritis in the rabbit and on the relationship of aseptic inflammation to infection rate. Yale J Biol Med. 1966 Oct;39(2):119–128. [PMC free article] [PubMed] [Google Scholar]
- Nakata M. M., Silvers J. H., George W. L. Group G streptococcal arthritis. Arch Intern Med. 1983 Jul;143(7):1328–1330. [PubMed] [Google Scholar]
- Rolston K. V., LeFrock J. L., Schell R. F. Activity of nine antimicrobial agents against Lancefield group C and group G streptococci. Antimicrob Agents Chemother. 1982 Nov;22(5):930–932. doi: 10.1128/aac.22.5.930. [DOI] [PMC free article] [PubMed] [Google Scholar]