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. 1986 May;29(5):803–806. doi: 10.1128/aac.29.5.803

Antimicrobial activity of borate-buffered solutions.

R D Houlsby, M Ghajar, G O Chavez
PMCID: PMC284157  PMID: 3729341

Abstract

A minimal salts medium adjusted to physiological pH and osmolality was buffered with either 0.3% phosphate or 1.2% borate and evaluated for antimicrobial activity. The borate-buffered medium, either with or without a carbon source, exhibited significant antimicrobial activity against 15 Pseudomonas strains, 12 strains of enteric bacteria, and 7 strains of staphylococci. The borate-buffered system appears suitable for use as a generic vehicle for ophthalmic pharmaceutical agents.

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Selected References

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