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. 1991 Jun;35(6):1219–1224. doi: 10.1128/aac.35.6.1219

Effect of beta-lactamase inhibitors on the activities of various beta-lactam agents against anaerobic bacteria.

H M Wexler 1, E Molitoris 1, S M Finegold 1
PMCID: PMC284314  PMID: 1929265

Abstract

The in vitro activities of several new beta-lactam-beta-lactamase inhibitor combinations (piperacillin plus tazobactam, ceftizoxime and cefonicid with sulbactam and clavulanic acid, and ampicillin plus 8 micrograms of sulbactam per ml) were tested with anaerobic bacteria and compared with known beta-lactam-beta-lactamase inhibitor combinations and other potent antianaerobe agents. All the combinations tested (except for the cefonicid-inhibitor combinations) were active against almost all strains of the Bacteroides fragilis group. This report indicates that beta-lactamase inhibitors may improve the activity of beta-lactam agents with marginal activity against the B. fragilis group.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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