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. 1994 Jul;38(7):1641–1643. doi: 10.1128/aac.38.7.1641

Macrolide antibiotics protect against endotoxin-induced vascular leakage and neutrophil accumulation in rat trachea.

J Tamaoki 1, N Sakai 1, E Tagaya 1, K Konno 1
PMCID: PMC284605  PMID: 7979298

Abstract

We studied the effects of macrolides on lipopolysaccharide (LPS)-induced airway inflammation in the rat tracheal mucosa. Erythromycin and roxithromycin dose dependently inhibited microvascular leakage and neutrophil recruitment induced by LPS. This inhibitory action on vascular permeability was abolished by neutrophil depletion.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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