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. 1994 Jul;38(7):1678–1680. doi: 10.1128/aac.38.7.1678

Determination of antimicrobial susceptibilities of Canadian isolates of Haemophilus influenzae and characterization of their beta-lactamases. Canadian Haemophilus Study Group.

S R Scriver 1, S L Walmsley 1, C L Kau 1, D J Hoban 1, J Brunton 1, A McGeer 1, T C Moore 1, E Witwicki 1
PMCID: PMC284617  PMID: 7979309

Abstract

Susceptibility testing of 1,688 Haemophilus influenzae isolates found 484 ampicillin-resistant strains; 474 strains (28.4%) were beta-lactamase positive, and 5 strains (0.4%) were non-beta-lactamase producers. Restriction enzyme digestion of the beta-lactamase amplicon determined that, of 157 strains, 11 (7.0%) contained ROB-1 beta-lactamase and 146 (93.0%) contained a TEM-type beta-lactamase.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Daum R. S., Murphey-Corb M., Shapira E., Dipp S. Epidemiology of rob beta-lactamase among ampicillin-resistant Haemophilus influenzae isolates in the United States. J Infect Dis. 1988 Mar;157(3):450–455. doi: 10.1093/infdis/157.3.450. [DOI] [PubMed] [Google Scholar]
  2. Jacoby G. A., Sutton L. beta-Lactamases and beta-lactam resistance in Escherichia coli. Antimicrob Agents Chemother. 1985 Nov;28(5):703–705. doi: 10.1128/aac.28.5.703. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Jorgensen J. H. Update on mechanisms and prevalence of antimicrobial resistance in Haemophilus influenzae. Clin Infect Dis. 1992 May;14(5):1119–1123. doi: 10.1093/clinids/14.5.1119. [DOI] [PubMed] [Google Scholar]
  4. Juteau J. M., Levesque R. C. Sequence analysis and evolutionary perspectives of ROB-1 beta-lactamase. Antimicrob Agents Chemother. 1990 Jul;34(7):1354–1359. doi: 10.1128/aac.34.7.1354. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Rubin L. G., Medeiros A. A., Yolken R. H., Moxon E. R. Ampicillin treatment failure of apparently beta-lactamase-negative Haemophilus influenzae type b meningitis due to novel beta-lactamase. Lancet. 1981 Nov 7;2(8254):1008–1010. doi: 10.1016/s0140-6736(81)91214-9. [DOI] [PubMed] [Google Scholar]
  6. Scriver S. R., Low D. E., Simor A. E., Toye B., McGeer A., Jaeger R. Broth microdilution testing of Haemophilus influenzae with haemophilus test medium versus lysed horse blood broth. Canadian Haemophilus Study Group. J Clin Microbiol. 1992 Sep;30(9):2284–2289. doi: 10.1128/jcm.30.9.2284-2289.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Sutcliffe J. G. Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322. Proc Natl Acad Sci U S A. 1978 Aug;75(8):3737–3741. doi: 10.1073/pnas.75.8.3737. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Sykes R. B., Matthew M., O'Callaghan C. H. R-factor mediated beta-lactamase production by Haemophilus influenzae. J Med Microbiol. 1975 Aug;8(3):437–441. doi: 10.1099/00222615-8-3-437. [DOI] [PubMed] [Google Scholar]
  9. Tremblay L. D., L'Ecuyer J., Provencher P., Bergeron M. G. Susceptibility of Haemophilus influenzae to antimicrobial agents used in Canada. Canadian Study Group. CMAJ. 1990 Nov 1;143(9):895–901. [PMC free article] [PubMed] [Google Scholar]
  10. Turk D. C. The pathogenicity of Haemophilus influenzae. J Med Microbiol. 1984 Aug;18(1):1–16. doi: 10.1099/00222615-18-1-1. [DOI] [PubMed] [Google Scholar]

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