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Figure.
Axial sections on single photon emission computed tomography through cerebellum, basal ganglia, and parietal region in case 2 (A) showing widespread reduction in cortical perfusion, and in age matched, healthy subject (B) for comparison
Acknowledgments
We thank Professor Ian Bone and Dr William Durward for giving their permission to publish these cases. The histopathological examinations were performed at the National CJD Surveillance Unit by Dr James Ironside.
See editorial by Pocchiari and p 577
Footnotes
Funding: None.
Conflicts of interest: None.
References
- 1.Will RG, Ironside JW, Zeidler M, Cousens SN, Estibeiro K, Alperovitch A, et al. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet. 1996;347:921–925. doi: 10.1016/s0140-6736(96)91412-9. [DOI] [PubMed] [Google Scholar]
- 2.Will RG, Zeidler M. Diagnosing Creutzfeldt-Jakob disease. BMJ. 1996;313:833–834. doi: 10.1136/bmj.313.7061.833. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3.Will RG, Zeidler M, Brown P, Harrington M, Lee KH, Kenney KL. Cerebrospinal-fluid test for new-variant Creutzfeldt-Jakob disease. Lancet. 1996;348:955. doi: 10.1016/s0140-6736(96)24040-1. [DOI] [PubMed] [Google Scholar]
- 4.Hill AF, Zeidler M, Ironside J, Collinge J. Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy. Lancet. 1997;349:99–100. doi: 10.1016/S0140-6736(97)24002-X. [DOI] [PubMed] [Google Scholar]
- 5.Kirk A, Ang LC. Unilateral Creutzfeldt-Jakob disease presenting as rapidly progressive aphasia. Can J Neur Sci. 1994;21:350–352. doi: 10.1017/s0317167100040944. [DOI] [PubMed] [Google Scholar]