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. 1994 Sep;38(9):2204–2206. doi: 10.1128/aac.38.9.2204

Therapeutic efficacy of lanoconazole, a new imidazole antimycotic agent, for experimental cutaneous candidiasis in guinea pigs.

Y Niwano 1, A Seo 1, K Kanai 1, H Hamaguchi 1, K Uchida 1, H Yamaguchi 1
PMCID: PMC284713  PMID: 7811048

Abstract

The therapeutic efficacy of 1% cream and 1% solution of lanoconazole, a new imidazole antimycotic agent, in the model of cutaneous candidiasis in prednisolone-treated guinea pigs was evaluated in comparison with that of comparable formulations of bifonazole. Each preparation was topically applied once a day for 3 consecutive days, starting on the fifth day postinfection, and quantitative culture study wsa conducted on the ninth day postinfection. Both formulations of lanoconazole were much more highly effective in terms of eradication of fungi than the bifonazole formulations.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Domon M. H., Mathieu L. G., de Repentigny J. Changes in the activity of antifungals in mixed cultures of bacteria and yeasts. Can J Microbiol. 1981 Aug;27(8):843–846. doi: 10.1139/m81-130. [DOI] [PubMed] [Google Scholar]
  2. Gilliland D., Li Wan Po A., Scott E. The bactericidal activity of a methyl and propyl parabens combination: isothermal and non-isothermal studies. J Appl Bacteriol. 1992 Mar;72(3):252–257. doi: 10.1111/j.1365-2672.1992.tb01831.x. [DOI] [PubMed] [Google Scholar]
  3. Ohmi T., Konaka S., Uchida M., Yamaguchi H. Antifungal activity of the new agent latoconazole in two tinea models. Arzneimittelforschung. 1991 Aug;41(8):847–851. [PubMed] [Google Scholar]
  4. Oka H., Niwano Y., Ohmi T., Tanaka T., Uchida M., Yamaguchi H. Therapeutic efficacy of latoconazole in formulations of clinical use on experimental dermatophytosis in guinea pigs. Arzneimittelforschung. 1992 Mar;42(3):345–349. [PubMed] [Google Scholar]
  5. Tong C. H., Draughon F. A. Inhibition by antimicrobial food additives of ochratoxin A production by Aspergillus sulphureus and Penicillium viridicatum. Appl Environ Microbiol. 1985 Jun;49(6):1407–1411. doi: 10.1128/aem.49.6.1407-1411.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]

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