Table 1.
Comparison of median CIMT and presence of carotid artery plaques by HIV and HCV infection status among 1675 Women’s Interagency HIV Study participants studied between April 2004 and September 2005.
| CIMT | Carotid artery plaques | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ratio of median values (95% CI) | OR (95% CI) of presence of ≥ 1 plaque | ||||||||
| N | Median (µm IQR) |
Unadjusted | Adjusted for age and race |
Adjusted for age, race and CVD risk factorsa |
Prevalence | Unadjusted | Adjusted for age and race |
Adjusted for age, race and CVD risk factorsa |
|
| HCV+/HIV+ | 220 | 748 (691, 829) | 1.08 (1.05, 1.10) | 0.98 (0.96, 0.99) | 0.97 (0.95, 0.99) | 21% | 4.28 (2.58, 7.09) | 1.87 (1.10, 3.19) | 1.64 (0.91, 2.94) |
| HCV+/HIV− | 53 | 753 (672, 834) | 1.08 (1.03, 1.12) | 0.97 (0.94, 1.01) | 0.97 (0.93, 1.00) | 13% | 2.40 (0.99, 5.81) | 0.96 (0.38, 2.42) | 0.77 (0.29, 2.07) |
| HCV−/HIV+ | 950 | 698 (642, 764) | 1.00 (0.98, 1.02) | 0.97 (0.96, 0.99) | 0.98 (0.97, 0.99) | 8% | 1.33 (0.84, 2.10) | 1.00 (0.62, 1.61) | 1.10 (0.66, 1.82) |
| HCV−/HIV− | 452 | 701 (641, 767) | 1 (reference) | 1 (ref) | 1 (ref) | 6% | 1 (ref) | 1 (ref) | 1 (ref) |
CI, confidence interval; CIMT,carotid artery intima-media thickness; CVD, cardiovascular disease; HCV, hepatitis C virus; IQR, interquartile range; OR, odds ratio.
a
Adjusted for enrollment cohort (1994–1995 or 2001–2002), age (per 10 years), race (African-American, Hispanic, Caucasian), enrollment cohort, menopause status, number of years reporting smoking, systolic and diastolic blood pressure, total cholesterol, HDL-cholesterol, and diabetes status.