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. Author manuscript; available in PMC: 2010 Mar 31.
Published in final edited form as: Laryngoscope. 2007 Jan;117(1):86–91. doi: 10.1097/01.mlg.0000244182.81768.31

Fig. 3.

Fig. 3

Interleukin (IL)-8 production in NL-20 cells is significantly inhibited by nuclear factor (NF)-κB inhibitors. Peptidoglycan-polysaccharides (PGPS) at 0.5 μg/mL significantly increased activity of both IL-8 and NF-κB reporter genes in NL-20 cells (A, *P < .05). PGPS-induced IL-8 promoter activity was significantly inhibited by pyrrolidine dithiocarbamate and IκBαM in NL-20 cells by luciferase assays (B, *P < .05). Similar results were also observed in rat middle ear epithelial cells (MEECs) (C) and mouse MEECs (D). Med = medium.