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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Genesis. 2009 Jun;47(6):409–413. doi: 10.1002/dvg.20515

Figure 2. The Tbx18-Cre transgene has expression specifically in the lower urinary tract.

Figure 2

At E12.5, whole-mount β-galactosidase assay revealed the occurrence of Cre-mediated loxP recombination in the developing ureteric stalk but not in the metanephros proper (A). The dotted line outlines the metanephric mesenchyme (MM). UB: Ureteric bud. At E15.5, blue cells were observed in the ureter and bladder (BL) but not in the kidney or urethra (UT) (B). The same pattern of Cre expression continues to birth (C).