Skip to main content
NCBI home page
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1969 May;98(2):605–610. doi: 10.1128/jb.98.2.605-610.1969

Carbohydrate Accumulation and Metabolism in Escherichia coli: the Close Linkage and Chromosomal Location of ctr Mutations

Richard J Wang a,1, Helvise G Morse a, M L Morse a
PMCID: PMC284861  PMID: 4891263

Abstract

Six pleiotropic ctr mutations of Escherichia coli, affecting the ability to utilize 10 carbohydrates, were found to be closely linked to one another and to the mutation of strain MM6 causing lack of enzyme 1 of the phosphotransferase system. These mutations are located at 46 to 47 min on the E. coli map. Preliminary biochemical evidence indicates that the ctr mutants also lack enzyme 1, although they have a different phenotype from MM6.

Full text

PDF
605

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Eggertsson G., Adelberg E. A. Map positions and specificities of suppressor mutations in Escherichia coli K-12. Genetics. 1965 Aug;52(2):319–340. doi: 10.1093/genetics/52.2.319. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Fox C. F., Wilson G. The role of a phosphoenolpyruvate-dependent kinase system in beta-glucoside catabolism in Escherichia coli. Proc Natl Acad Sci U S A. 1968 Mar;59(3):988–995. doi: 10.1073/pnas.59.3.988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. KUNDIG W., GHOSH S., ROSEMAN S. PHOSPHATE BOUND TO HISTIDINE IN A PROTEIN AS AN INTERMEDIATE IN A NOVEL PHOSPHO-TRANSFERASE SYSTEM. Proc Natl Acad Sci U S A. 1964 Oct;52:1067–1074. doi: 10.1073/pnas.52.4.1067. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Rothman J. L. Transduction studies on the relation between prophage and host chromosome. J Mol Biol. 1965 Jul;12(3):892–912. doi: 10.1016/s0022-2836(65)80336-9. [DOI] [PubMed] [Google Scholar]
  5. Scarborough G. A., Rumley M. K., Kennedy E. P. The function of adenosine 5'-triphosphate in the lactose transport system of Escherichia coli. Proc Natl Acad Sci U S A. 1968 Jul;60(3):951–958. doi: 10.1073/pnas.60.3.951. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Schaefler S., Maas W. K. Inducible system for the utilization of beta-glucosides in Escherichia coli. II. Description of mutant types and genetic analysis. J Bacteriol. 1967 Jan;93(1):264–272. doi: 10.1128/jb.93.1.264-272.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Tanaka S., Fraenkel D. G., Lin E. C. The enzymatic lesion of strain MM-6, a pleiotropic carbohydrate-negative mutant of Escherichia coli. Biochem Biophys Res Commun. 1967 Apr 7;27(1):63–67. doi: 10.1016/s0006-291x(67)80040-8. [DOI] [PubMed] [Google Scholar]
  8. Taylor A. L., Trotter C. D. Revised linkage map of Escherichia coli. Bacteriol Rev. 1967 Dec;31(4):332–353. doi: 10.1128/br.31.4.332-353.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Wang R. J., Morse M. L. Carbohydrate accumulation and metabolism in Escherichia coli. I. Description of pleiotropic mutants. J Mol Biol. 1968 Feb 28;32(1):59–66. doi: 10.1016/0022-2836(68)90145-9. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES