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. 1970 Nov;104(2):1014–1016. doi: 10.1128/jb.104.2.1014-1016.1970

Inhibition by Phenylalanine of Thiazole Biosynthesis in Escherichia coli

Akio Iwashima 1, Yoshitsugu Nose 1
PMCID: PMC285084  PMID: 4923061

Abstract

Phenylalanine inhibited thiazole biosynthesis in a thiamine-regulatory mutant of Escherichia coli, and the inhibition was overcome by tyrosine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brown K. D., Doy C. H. Control of three isoenzymic 7-phospho-2-oxo-3-deoxy-Darabino-heptonate-D-erythrose-4-phosphate lyases of Escherichia coli W and derived mutants by repressive and "inductive" effects of the aromatic amino acids. Biochim Biophys Acta. 1966 Apr 12;118(1):157–172. doi: 10.1016/s0926-6593(66)80153-4. [DOI] [PubMed] [Google Scholar]
  2. DAVIS B. D., MINGIOLI E. S. Mutants of Escherichia coli requiring methionine or vitamin B12. J Bacteriol. 1950 Jul;60(1):17–28. doi: 10.1128/jb.60.1.17-28.1950. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. DEMPSEY W. B. CONTROL OF PYRIDOXINE BIOSYNTHESIS IN ESCHERICHIA COLI. J Bacteriol. 1965 Aug;90:431–437. doi: 10.1128/jb.90.2.431-437.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Doy C. H., Brown K. D. Control of aromatic biosynthesis: the multiplicity of 7-phospho-2-oxo-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating) in Escherichia coli W. Biochim Biophys Acta. 1965 Jul 8;104(2):377–389. doi: 10.1016/0304-4165(65)90343-0. [DOI] [PubMed] [Google Scholar]
  5. Gibson F., Pittard J. Pathways of biosynthesis of aromatic amino acids and vitamins and their control in microorganisms. Bacteriol Rev. 1968 Dec;32(4 Pt 2):465–492. [PMC free article] [PubMed] [Google Scholar]
  6. IMSANDE J. A COMPARATIVE STUDY OF THE REGULATION OF PYRIDINE NUCLEOTIDE FORMATION. Biochim Biophys Acta. 1964 Mar 16;82:445–453. doi: 10.1016/0304-4165(64)90436-2. [DOI] [PubMed] [Google Scholar]
  7. Iwashima A., Kawasaki T., Nakamura M., Nose Y. Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli. J Vitaminol (Kyoto) 1968 Sep 10;14(3):203–210. doi: 10.5925/jnsv1954.14.203. [DOI] [PubMed] [Google Scholar]
  8. Kawasaki T., Nose Y. Thiamine regulatory mutants in Escherichia coli. J Biochem. 1969 Mar;65(3):417–425. doi: 10.1093/oxfordjournals.jbchem.a129029. [DOI] [PubMed] [Google Scholar]
  9. Kawasi T., Iwashima A., Nose Y. Regulation of thiamine biosynthesis in Escherichia coli. J Biochem. 1969 Mar;65(3):407–416. doi: 10.1093/oxfordjournals.jbchem.a129028. [DOI] [PubMed] [Google Scholar]
  10. MOYED H. S. INHIBITION OF THE BIOSYNTHESIS OF THE PYRIMIDINE PORTION OF THIAMINE BY ADENOSINE. J Bacteriol. 1964 Oct;88:1024–1029. doi: 10.1128/jb.88.4.1024-1029.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Newell P. C., Tucker R. G. Biosynthesis of the pyrimidine moiety of thiamine. A new route of pyrimidine biosynthesis involving purine intermediates. Biochem J. 1968 Jan;106(1):279–287. doi: 10.1042/bj1060279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Newell P. C., Tucker R. G. The control mechanism of thiamine biosynthesis a model for the study of control of converging pathways. Biochem J. 1966 Aug;100(2):517–524. doi: 10.1042/bj1000517. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. PAI C. H., LICHSTEIN H. C. THE BIOSYNTHESIS OF BIOTIN IN MICROORGANISMS. 3. THE BIOSYNTHESIS OF (+)-BIOTIN FROM DESTHIOBIOTIN AND ITS CONTROL IN ESCHERICHIA COLI. Biochim Biophys Acta. 1965 Apr 12;100:43–49. doi: 10.1016/0304-4165(65)90425-3. [DOI] [PubMed] [Google Scholar]

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