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. 1972 Feb;109(2):560–564. doi: 10.1128/jb.109.2.560-564.1972

Identification of Competence-Repressing Factors During Log-Phase Growth of Haemophilus influenzae

Donald H Miller a,1, P C Huang a,2
PMCID: PMC285177  PMID: 4333608

Abstract

Metabolic factors that suppress development of competence in Haemophilus influenzae during growth in the synthetic medium MIc have been identified. These include inosine, nicotinamide adenine dinucleotide, glycerol, and uracil. It is also possible to initiate competence in the presence of these substances if the oxygen tension in the culture is temporarily reduced.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anagnostopoulos C., Spizizen J. REQUIREMENTS FOR TRANSFORMATION IN BACILLUS SUBTILIS. J Bacteriol. 1961 May;81(5):741–746. doi: 10.1128/jb.81.5.741-746.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BARNHART B. J., HERRIOTT R. M. PENETRATION OF DEOXYRIBONUCLEIC ACID INTO HEMOPHILUS INFLUENZAE. Biochim Biophys Acta. 1963 Sep 17;76:25–39. [PubMed] [Google Scholar]
  3. Caster J. H., Postel E. H., Goodgal S. H. Competence mutants: isolation of transformation deficient strains of Haemophilus influenzae. Nature. 1970 Aug 1;227(5257):515–517. doi: 10.1038/227515a0. [DOI] [PubMed] [Google Scholar]
  4. DOBROGOSZ W. J. THE INFLUENCE OF NITRATE AND NITRITE REDUCTION ON CATABOLITE REPRESSION IN ESCHERICHIA COLI. Biochim Biophys Acta. 1965 May 4;100:553–566. doi: 10.1016/0304-4165(65)90025-5. [DOI] [PubMed] [Google Scholar]
  5. Flavell R. B., Woodward D. O. The regulation of synthesis of Krebs cycle enzymes in Neurospora by catabolite and end product repression. Eur J Biochem. 1970 Apr;13(3):548–553. doi: 10.1111/j.1432-1033.1970.tb00959.x. [DOI] [PubMed] [Google Scholar]
  6. Herriott R. M., Meyer E. M., Vogt M. Defined nongrowth media for stage II development of competence in Haemophilus influenzae. J Bacteriol. 1970 Feb;101(2):517–524. doi: 10.1128/jb.101.2.517-524.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Herriott R. M., Meyer E. Y., Vogt M., Modan M. Defined medium for growth of Haemophilus influenzae. J Bacteriol. 1970 Feb;101(2):513–516. doi: 10.1128/jb.101.2.513-516.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. LEONARD C. G., MATTHEIS D. K., MATTHEIS M. J., HOUSEWRIGHT R. D. TRANSFORMATION TO PROTOTROPHY AND POLYGLUTAMIC ACID SYNTHESIS IN BACILLUS LICHENIFORMIS. J Bacteriol. 1964 Jul;88:220–225. doi: 10.1128/jb.88.1.220-225.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. LIE S. STUDIES ON THE PHENOTYPIC EXPRESSION OF COMPETENCE IN NEISSERIA MENINGITIDIS. Acta Pathol Microbiol Scand. 1965;64:119–129. doi: 10.1111/apm.1965.64.1.119. [DOI] [PubMed] [Google Scholar]
  10. Miller D. H., Huang P. C. Time-dependent effects of inosine on competence development in Haemophilus influenzae. J Bacteriol. 1970 Nov;104(2):775–779. doi: 10.1128/jb.104.2.775-779.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Moses V., Prevost C. Catabolite repression of beta-galactosidase synthesis in Escherichia coli. Biochem J. 1966 Aug;100(2):336–353. doi: 10.1042/bj1000336. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Spencer H. T., Herriott R. M. Development of competence of Haemophilus influenzae. J Bacteriol. 1965 Oct;90(4):911–920. doi: 10.1128/jb.90.4.911-920.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]

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