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. 1973 Jun;114(3):1034–1039. doi: 10.1128/jb.114.3.1034-1039.1973

Distribution of Ribosomal Ribonucleic Acid Cistrons Among Yeast Chromosomes

Siwo R De Kloet 1
PMCID: PMC285361  PMID: 4576396

Abstract

High-molecular-weight deoxyribonucleic acid (DNA) of Saccharomyces carls bergensis has been fractionated by sucrose density gradient centrifugation. The main DNA fraction has an average molecular weight of about 500 × 106. A major fraction of the DNA molecules containing sequences homologous to ribosomal ribonucleic acid (RNA) sediments as material of this molecular weight. The remainder sediments as material of a molecular weight of about 250 × 106. The latter fraction contains relatively more ribosomal RNA cistrons than the former. Studies on the buoyant density of high-molecular-weight DNA homologous to ribosomal RNA have led to the conclusion that the ribosomal RNA cistrons occur in groups attached to a relatively large amount of nonribosomal RNA and suggest that ribosomal RNA cistrons are distributed over a number of yeast chromosomes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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