FIG. 2.

Human telomerase reverse transcriptase (hTERT) alternative splice variant patterns in thyroid tumors. (A) Gels demonstrating hTERT alternative splice variant patterns present in representative thyroid tumors. One blank lane in FA represents an hTERT-negative tumor. (B) Plots of relative proportions of full-length (F), α⁻ deletion, and β⁻/α⁻β⁻ deletion transcripts for the eight thyroid tumor types (only tumor types that exhibited the combination of α⁻β⁻ deletion are labeled β⁻/α⁻β⁻). AN, adenomatoid nodule; FA, follicular adenoma; FC, follicular carcinoma; FVPTC, follicular variant of papillary thyroid carcinoma; HA, Hürthle cell adenoma; HC, Hürthle cell carcinoma; LcT, lymphocytic thyroiditis nodule; PTC, papillary thyroid carcinoma.