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. 2010 Feb 2;115(16):3224–3230. doi: 10.1182/blood-2009-11-251595

Table 2.

Morbidity and mortality after transplantation

Related, no. Unrelated, no. Combined no. (%)
Nonfatal toxicity up to day 100*
    ALT elevation, grade IV 8 5 13 (11)
    AST elevation, grade IV 4 2 6 (5)
    Bilirubin elevation, grade IV 4 4 8 (7)
    Serum creatinine, grade III 3 3 6 (5)
    Reversible VOD 7 1 8 (7)
    Hemorrhagic cystitis 1 11 12 (10)
    Pericardial effusion 3 0 3 (3)
    Subdural hematoma 1 0 1 (1)
Cause of death
    Related to relapse or progression 21 10 31 (26)
    Related to transplantation
        Graft failure 0 1 1 (1)
        VOD 2 0 2 (2)
        Noninfectious pneumonia 1 1 2 (2)
        Sepsis/bacterial infection 2 1 3 (3)
        Hemorrhage 2 2 4 (3)
        Refractory GVHD 2 1 3 (3)
        Multisystem organ failure 3 2 5 (4)

ALT indicates alanine aminotransferase; and AST, aspartate aminotransferase.

*

Only highest-grade toxicities are presented.