Table 2.
Percentage of papillomas with different degrees of atypia at 30 weeks of promotion
| Genotype | Regular Papillomas 1 |
Moderately dysplastic papillomas 2 |
Severely dysplastic papillomas 3 |
Intrapapilloma carcinoma 4 |
|---|---|---|---|---|
| K5-CDK4 (n=15) | 1/15 (7%) | 2/15 (13%) | 4/15 (27%) | 8/15 (53%) |
| Wild type (n=17) | 7/17 (41%) | 8/17 (47%) | 0/17 (0%) | 2/17 (12%) |
Chi-square, p=0.0013
1
No atypia in basal layer
2
Atypia in basal and some suprabasal layer
3
Atypia in all layers
4
Marked atypia in all layers and lack of differentiation pattern (carcinoma in situ). Areas of microinvasion.